Proton Pump Inhibitors & Kidney Damage

The Truth About Acute Interstitial Nephritis & Certain Heartburn Medications

  • The use of Nexium ®, Prilosec ® , Prevacid ® and other proton pump inhibitor drugs (PPIs) may increase the risk of developing Acute Interstitial Nephritis by almost 12,000%. Mei-Ling Blank, et al, A Nationwide Nested Case-Control Study Indicates An Increased Risk Of Acute Interstitial Nephritis With Proton Pump Inhibitor Use (2014).
  • One study found that PPIs were the “most commonly identified cause” of Acute Interstitial Nephritits. Ian Simpson, et al., Nephrology, Proton Pump Inhibitors And Acute Interstitial Nephritis: Report And Analysis Of 15 Cases (2006).
  • The first reported case of Acute Interstitial Nephritis caused by a PPI drug was documented in 1992, but the manufacturers of PPIs failed to even mention this risk until 2014. Ruffenach, et al., The American Journal of Medicine, Acute Interstitial Nephritis Due To Omeprazole (1992).
  • PPI-Induced Acute Interstitial Nephritis can occur in a relative short period of time. Indian J. Nephrol., Acute Interstitial Nephritis Due To Proton Pump Inhibitors (2013).
  • Acute Interstitial Nephritis is usually diagnosed after a kidney biopsy.

If you or a loved one took a PPI and developed Acute Interstitial Nephritis, Acute Kidney/Renal Failure or had a kidney biopsy, call us toll free (877-704-7674) for a free legal consultation from a lawyer who has handled thousands of cases involving defective drugs and medical devices.  Our clients owe us nothing for the investigation or prosecution of their case unless we obtain a recovery for them.