Proton Pump Inhibitors And Kidney Damage

The Truth About Acute Interstitial Nephritis & Certain Heartburn Medications

  • The use of Nexium ®, Prilosec ® , Prevacid ® and other proton pump inhibitor drugs (PPIs) may increase the risk of developing Acute Interstitial Nephritis by almost 12,000%. Mei-Ling Blank, et al, A Nationwide Nested Case-Control Study Indicates An Increased Risk Of Acute Interstitial Nephritis With Proton Pump Inhibitor Use (2014).
  • One study found that PPIs were the “most commonly identified cause” of Acute Interstitial Nephritis. Ian Simpson, et al., Nephrology, Proton Pump Inhibitors And Acute Interstitial Nephritis: Report And Analysis Of 15 Cases (2006).
  • The first reported case of Acute Interstitial Nephritis caused by a PPI drug was documented in 1992, but the manufacturers of PPIs failed to even mention this risk until 2014. Ruffenach, et al., The American Journal of Medicine, Acute Interstitial Nephritis Due To Omeprazole (1992).
  • PPI-Induced Acute Interstitial Nephritis can occur in a relative short period of time. Indian J. Nephrol., Acute Interstitial Nephritis Due To Proton Pump Inhibitors (2013).
  • Acute Interstitial Nephritis is usually diagnosed after a kidney biopsy.

If you or a loved one took a PPI and developed Acute Interstitial Nephritis, Acute Kidney/Renal Failure or had a kidney biopsy, call us toll free (877-704-7674) for a free legal consultation from a lawyer who has handled thousands of cases involving defective drugs and medical devices.  Our clients owe us nothing for the investigation or prosecution of their case unless we obtain a recovery for them.

This web site is designed for general information only. The information presented at this site should not be construed to be formal legal advice nor the formation of a lawyer/client relationship. The choice of a lawyer is an important decision and should not be based solely upon advertisements. Past results afford no guarantee of future results. Every case is different and must be judged on its own merits.  Attorneys David Summers and Aaron Johnson are licensed in Missouri and Kansas; however our attorneys have handled cases nationwide, including mass tort claims that are filed in federal courts.*  Always consult your doctor before making any change in medication.

* In order to represent clients in states where the attorneys are not licensed, they must be granted admission pro hac vice or associate with local counsel.

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